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Some patients experience itching or tenderness for 2448 hours post-injection

Tirzepatide, which targets both GLP-1 and GIP receptors, tends to produce similar gastrointestinal side effects but may have different impacts on gut motility patterns

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[40] [41] Mechanism of action [edit] Tirzepatide has a greater affinity to GIP receptors than to GLP-1 receptors, and this dual agonist behavior has been shown to produce greater reductions of hyperglycemia compared to a selective GLP-1 receptor agonist

Prices drop to as low as $249 per month for both injections and maintenance-dose pills under a 12-month plan